Generic Neoral (Cyclosporine)
Neoral
Cyclosporine is used to prevent organ rejection after a kidney, liver, or heart transplant.
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25 mg x 10 pills
$78.99
$7.90
$0.00
25 mg x 20 pills
$135.99
$6.80
$22.00
25 mg x 30 pills
$186.99
$6.23
$50.10
25 mg x 60 pills
$339.99
$5.67
$133.80
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100 mg x 10 pills
$154.99
$15.50
$0.00
100 mg x 20 pills
$262.99
$13.15
$47.00
100 mg x 30 pills
$358.99
$11.97
$105.90
Product Description

Neoral - something is

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Common use

Cyclosporine lowers your body's immune system. The immune system helps your body fight infections. The immune system can also fight or "reject" a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader.

Cyclosporine is used to prevent organ rejection after a kidney, liver, or heart transplant.

Dosage and direction

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended.

You may take cyclosporine with or without food, but take it the same way each time. Cyclosporine should be given in two separate doses each day. Try to take the medication at the same dosing times each day. Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon.



Precautions

Avoid exposure to sunlight, sunlamps, or tanning beds. Cyclosporine can make your skin more sensitive to sunlight, and a sunburn may result. Wear protective clothing and use sunscreen (SPF 15 or higher) when you are outdoors.

If you are being treated for psoriasis, you should not receive light therapy (PUVA or UVB) or radiation treatments while you are receiving cyclosporine. Make sure all doctors involved in your care know you are taking cyclosporine.



Contraindications

You should not use this medication if you are allergic to cyclosporine. You may not be able to use cyclosporine if you have:

kidney disease;

untreated or uncontrolled high blood pressure; or

any type of cancer.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take cyclosporine:

psoriasis that has been treated with PUVA, UVB, radiation, methotrexate (Trexall), or coal tar; or

if you are also taking an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), and others.

It is not known whether cyclosporine is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Cyclosporine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.



Possible side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

urinating less than usual or not at all;

drowsiness, confusion, mood changes, increased thirst;

swelling, weight gain, feeling short of breath;

blurred vision, headache or pain behind your eyes, sometimes with vomiting;

seizure (convulsions);

muscle pain or weakness, fast heart rate, feeling light-headed;

signs of infection such as fever, chills, sore throat, flu symptoms;

pale skin, easy bruising or bleeding, unusual weakness; or

nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

tremors or shaking;

increased hair growth;

headache or body pain;

diarrhea, constipation, vomiting; or

numbness or tingly feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.



Drug interaction

Many drugs can interact with cyclosporine. Below is just a partial list. Tell your doctor about all other medications you are using, especially: etoposide (VePesid, Etopophos); lithium (Eskalith, Lithobid); methotrexate (Rheumatrex, Trexall); nefazodone; repaglinide (Prandin); St. John's wort;

an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik);

a heart or blood pressure medication such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro, Avalide), losartan (Cozaar, Hyzaar), valsartan (Diovan), telmisartan (Micardis), or olmesartan (Benicar);

medicines used to treat ulcerative colitis, such as mesalamine (Pentasa) or sulfasalazine (Azulfidine);

other medicines used to prevent organ transplant rejection, such as sirolimus (Rapamune) or tacrolimus (Prograf);

pain or arthritis medicines such as aspirin (Anacin, Excedrin), acetaminophen (Tylenol), diclofenac (Voltaren), etodolac (Lodine), ibuprofen (Advil, Motrin), indomethacin (Indocin), naproxen (Aleve, Naprosyn), and others;

IV antibiotics such as amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet), amikacin (Amikin), bacitracin (Baci-IM), capreomycin (Capastat), gentamicin (Garamycin), kanamycin (Kantrex), streptomycin, or vancomycin (Vancocin, Vancoled);

antiviral medicines such as adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir); or

cancer medicine such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), streptozocin (Zanosar), or tretinoin (Vesanoid).



Missed dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.



Overdose

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose can cause nausea, vomiting, pain in your upper stomach, loss of appetite, jaundice (yellowing of the skin or eyes), and urinating less than usual or not at all.

Storage

Store cyclosporine at room temperature away from moisture and heat.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. The specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Antibiotics

Antibiotics is one of most prescribed group of medications. Antibiotics are antibacterial (antimicrobial agents) that kills bacteria(bactericidal) or stop the growth of the bacteria(bacteriostatic action).

Antibiotics are used to treat bacterial infections and are not indicated for the viral infections. Currently there is a big variety of antibiotics available. All the antibiotics are divided into two main groups according to the action mechanism:

  • Antibiotics with bactericidal action(penicillins, cephalosporins, aminoglycoside)
  • Antibacterial with bacteriostatic action(macrolides, tetracyclines)

Penicillins and cephalospororins are the most prescribed group of antibiotics. They belong to half-synthetic beta lactam antibiotics. These antibiotics work by inhibiting the enzymes responsible for the production of peptidoglycan. Peptidoglycan is a biopolimer that is a main structural component of the bacterial cell wall. The blockage of peptidoglycan synthesis leads to the lysis of the microorganisms.

Another group of preparations are aminoglycosides. However, these antibiotics are prescribed in rare cases. The most of aminoglycosides possesses nephrotoxicity, ototoxicity and cab cause neuromuscular blockage. Bactericidal action of aminoglycosides is related to the interfering with the synthesis of proteins on the ribisomes in the microbial cells. When aminoglycosides are used with penicillins and cephalosporins the sinergism against gram-positive and gram-negative microorganisms is observed.

Among all bacteriostatic antibiotics macrolides and tetracyclines are the most indicated groups. Therapeutic effect of macrolides is associated with inhibiting the synthesis of proteins on the ribosomes in the microbial cell. As usual macrolides exert bacteriostatic action, however in high amounts are able to exert bactericidal action on some microorganisms. Besides antibacterial action, some macrolides possesses immunomodulatory and anti-inflammatory action.

Another group of bacteriostatic antibiotics are used less frequently as many microorganisms became resistant to the this type of antibiotics. Bacteriostatic effect of the tetracyclines is associated with inhibiting the synthesis of proteins. Tetracycline are indicated in clamydia infections, rickettsial disease, some zoonosis, severe acne.

Antibiotics are indicated and used only in the cases of the bacteria is sensitive to the antibiotics. There some specific tests like antibiogram that will help to determine the right antibiotic and corresponding dose.