Generic Lozol (Indapamide)
Lozol
Lozol is used to treat hypertension either alone or in combination with other high blood pressure medications.
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1,5 mg x 30 pills
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1,5 mg x 60 pills
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1,5 mg x 90 pills
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1,5 mg x 120 pills
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1,5 mg x 180 pills
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1,5 mg x 360 pills
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2,5 mg x 90 pills
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2,5 mg x 120 pills
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2,5 mg x 180 pills
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Product Description
Drug information provided by: IBM Micromedex. Also reported are erythema multiforme, Stevens-Johnson Syndrome, bullous eruptions, purpura, photosensitivity, Lozol, pneumonitis, anaphylactic reactions, agranulocytosis, leukopenia, thrombocytopenia and aplastic anemia. Call your doctor for medical advice about side effects. Foods high in potassium can also be helpful. This medicine may make your skin more sensitive to sunlight. Musculoskeletal: muscle cramps and spasms. Hidden categories: Template:drugs. You may want to take your dose before 6 p. Do not drive or operate heavy machinery until you know how it affects you. Lozol 2. Ann Intern Med ; This medication comes in tablet form and is usually taken once daily. Thiazide diuretics may also be used for other conditions as determined by your doctor. Be sure to tell oLzol doctor about any medications you are currently taking. Moreover, diuretics are known to cross the placental barrier and appear in cord blood. Drug information contained herein may be time sensitive. However, if adverse effects happen they can last for a long time. To find out if your medication is available as a Teva generic, contact your local pharmacy. Hypertension Research. Indapamide Interactions. Maximum daily dose is 5 mg. In these cases, a short course of diuretics may provide relief and may be appropriate. Monitor patient closely. Don't breastfeed a baby while using indapamide. The following information includes only the average doses Lkzol this medicine. But if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular medication schedule. Several Lozo are available to treat hypertension. Medications can interact with certain foods. Caution is advised in the combination of indapamide with lithium and nonantiarrhythmic drugs causing wave-burst arrhythmia astemizolebepridilIV erythromycinhalofantrinepentamidinesultoprideterfenadineand vincamine. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Overdose and treatment Signs and symptoms of overdose include GI irritation and hypermotility, diuresis, and lethargy, which may progress to coma. Although not all of these side effects may occur, if they do occur they may need medical attention. If a child unintentionally gets into indapamide, treatment will depend on age. Did you experience many side effects while taking this drug? These diuretics begin to work within 2 hours and produce their effect in 2- 6 hours. Diazoxide: Increases hyperglycemic, hypotensive, and hyperuricemic effects of diazoxide. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Indapamide Interactions. Avoid unnecessary exposure to the sun and tanning booths, and wear sunscreen and protective clothing while outdoors. You may also notice an increase in urine or in frequency of urination.
Common use

Lozol is a thiazide-like diuretic which contains an active substance benzamide-sulfonamide-indole (Indapamide). By its pharmacological properties it is similar to thiazide diuretics (changes of Na+ re-absorption in the vertical segment of the loop of Henle). Lozol increases excretion of Na+, Cl-, K+, and Mg2+ with urine. It is used to treat hypertension either alone or in combination with other high blood pressure medications. Long treatment with Lozol is required, a therapeutic effect observed after 1-2 weeks of use, maximum is reached in 8-12 weeks and keeps up to 8 weeks.



Dosage and direction

Take Lozol once a day in mornings before breakfast with or without food. The usual initial dose is 1.25 mg taken as a single daily dose. It may be increased up to 5 mg.



Precautions

Lozol and other diuretics stimulate excretion of slats and potassium with urine which may lead to considerable loss of the substances especially among elderly women. Hypopotasse signs are muscle weakness and rapid or irregular heartbeat. For compensation of the potassium loss, you may be recommended to eat potassium-rich foods or taking a potassium supplement. Risk of hypopotassemia increases when larger doses are used, in the patients with cirrhosis, and in those treated by corticosteroids or ACTH. Blood pressure, K+ serum, and creatinine tests should be done regularly, especially in the individuals with an irregular heartbeat or those on heart medications. Systematic control of blood K+, Na+, Mg2+, pH, glucose uric acid and residual nitrogen is required especially in patients with gout or high uric acid levels, liver disease, diabetes, or lupus erythematosus, kidney dysfunction.



Contraindications

Lozol cannot be administered in patients with hypersensitivity to its components, severe liver or kidney failure (anuria), hypopotassemia. High doses of Lozol cannot be used to treat edematous syndrome in the patients with cerebrovascular accident and decompensated diabetes with ketoacidosis. Lozol cannot be used in individuals with lactose intolerance, galactosemia, a syndrome of glucose malabsorption for the medication which contain lactose. Cautiousness should be exercised in individuals with impairments of water-electrolyte balance, moderate liver or kidney failure, ascites, coronary artery disease, heart failure, hyperuricemia (gout), hyperparathyroidism, pregnant or breastfeeding women in elderly or adolescents under 18 years of age.



Possible side effect

Frequency of side effects depends on the dose of Lozol. They may appear as agitation, anxiety, dizziness, headache, back pain, diarrhea, vomiting, abdominal pain, dry mouth, infection, irritability, muscle cramps or spasms, numbness in hands and feet, nervousness, nasal inflammation, pain, tension, fatigue, weakness, loss of energy or tiredness.



Drug interaction

Lozol may cause hypopotasseimia and hypomagnesemia. Fatal arrhythmias may develop in patients on digoxin (Lanoxin) due to toxicity. Cardiac arrhythmias are also caused by use of amiodarone (Cordarone) and indapamide. Elimination of lithium by kidneys decreases in patients treated by diuretics and hereby leads to increase of lithium toxicity.



Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.



Overdose

You need immediate medical attention in case of Lozol overdose which may express through such symptoms as electrolyte imbalance, nausea, stomach disorders, vomiting, weakness.



Storage

Tablets of Lozol should be stored at room temperature between 15-30 C (59-86 F).



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Antibiotics

Antibiotics is one of most prescribed group of medications. Antibiotics are antibacterial (antimicrobial agents) that kills bacteria(bactericidal) or stop the growth of the bacteria(bacteriostatic action).

Antibiotics are used to treat bacterial infections and are not indicated for the viral infections. Currently there is a big variety of antibiotics available. All the antibiotics are divided into two main groups according to the action mechanism:

  • Antibiotics with bactericidal action(penicillins, cephalosporins, aminoglycoside)
  • Antibacterial with bacteriostatic action(macrolides, tetracyclines)

Penicillins and cephalospororins are the most prescribed group of antibiotics. They belong to half-synthetic beta lactam antibiotics. These antibiotics work by inhibiting the enzymes responsible for the production of peptidoglycan. Peptidoglycan is a biopolimer that is a main structural component of the bacterial cell wall. The blockage of peptidoglycan synthesis leads to the lysis of the microorganisms.

Another group of preparations are aminoglycosides. However, these antibiotics are prescribed in rare cases. The most of aminoglycosides possesses nephrotoxicity, ototoxicity and cab cause neuromuscular blockage. Bactericidal action of aminoglycosides is related to the interfering with the synthesis of proteins on the ribisomes in the microbial cells. When aminoglycosides are used with penicillins and cephalosporins the sinergism against gram-positive and gram-negative microorganisms is observed.

Among all bacteriostatic antibiotics macrolides and tetracyclines are the most indicated groups. Therapeutic effect of macrolides is associated with inhibiting the synthesis of proteins on the ribosomes in the microbial cell. As usual macrolides exert bacteriostatic action, however in high amounts are able to exert bactericidal action on some microorganisms. Besides antibacterial action, some macrolides possesses immunomodulatory and anti-inflammatory action.

Another group of bacteriostatic antibiotics are used less frequently as many microorganisms became resistant to the this type of antibiotics. Bacteriostatic effect of the tetracyclines is associated with inhibiting the synthesis of proteins. Tetracycline are indicated in clamydia infections, rickettsial disease, some zoonosis, severe acne.

Antibiotics are indicated and used only in the cases of the bacteria is sensitive to the antibiotics. There some specific tests like antibiogram that will help to determine the right antibiotic and corresponding dose.